At the beginning, Sam Puckett is seen motorcycling down a street. She is in Los Angeles, saying she is 'looking for fun', due to Carly moving to Italy. Cat Valentine, a few moments later, rides a bike down the street and encounters two kids looking for a kitten named "Pawsley." She looks in a trash can and falls in, and pops out with the kitten, which the kids take and walk off. She drops her gum in the trash can and reaches back down to pick it up, but a garbage truck drives by and lifts up the trash can, with Cat still inside looking for her gum. Sam is standing nearby, eating a burrito and sees Cat get poured into the garbage truck. She throws her burrito into the street (a little sadly) and begins to run after the truck to tell the man driving that there is a girl inside.  Sam climbs inside the garbage truck when she cannot get the drivers attention and finds Cat flung upside down inside. She pulls Cat's head out of the garbage and stands her upright, to which Cat exclaims: "Wow! That was so fun!" Sam halfheartedly agrees. Cat recognizes Sam from iCarly and seems very excited to meet her, but Sam is worried about being stuck in the truck and tells Cat they have to get out. Just then, the garbage truck picks up another garbage can and dumps it into the truck with a loud noise. Cat nervously asks what the noises is and Sam says it's the sound of two girls about to be crushed by garbage. True to her ditsy nature, Cat says: "You don't mean us, right?" Sam tries to help Cat out of the truck, but Cat faints because she is scared. Sam saves an unconscious Cat from the truck.

After getting out of the truck, Sam wakes Cat by using a leaf blower on her.  Cat asks Sam where they are and what the horrible smell around them is. Sam informs her that the smell is the two of them because they went "swimming in garbage." Sam says she needs to find a place to hose herself off. To thank Sam for her help, Cat offers to let Sam come with her to her Nona's for a bath. The two pretend to be the daughters of a rich British doctor in order to get a ride in a limo to Nona's. After Sam showers, Sam meets one of Cat's neighbors, Dice, a preteen boy who deals various items, including "celebrity hair." As Cat goes nuts over Justin Bieber's hair and buys it, Dice notices Sam for the first time. Sam offers to sell some of her hair to balance out the cost of Cat's purchase. As Dice leaves, two kids push Cat's grandmother, Nona into the house. She, a part-time babysitter, laments over her inability to cope with such crazy children, and considers moving to Elderly Acres, a nursing home. Cat protests, but Nona is distracted from making her argument by Sam's presence, and agrees to let her stay for the night.

During a rough night's sleep on Cat's sofa-bed, complete with Nona's recurring sleepwalking and getting folded into the sofa itself, Sam admits to Cat that she is in no rush to go back to Seattle. As Carly is in Italy and her mom is "kind of a nut job," she chooses to travel around America on her motorcycle and "see where it takes her." Cat tries to tell Sam that it is she herself who has the power to control her journey and her destination, but phrases it wrong and confuses Sam.

The next morning, Nona asks Sam to take her to Elderly Acres, and Sam proceeds to do so. Cat panics and immediately runs over to the building with two kids and a baby that Nona was supposed to babysit. She figures out that Nona actually wants to stay, and asks her to come visit as much as she can. Meanwhile, Sam has the three kids ride on a nearby scooter, and also does voluntary tattoo work in the requested tattoo man's place, however, screws up at least one of the tattoo requests by tattooing a chicken leg on one man's arm.

Unbeknownst to her, the kids drive to Inside Out Burger, a restaurant, and order food there. They run into some trouble when they realize they do not have money to pay for it, and end up being chased around the parking lot by the manager.

Sam and Cat return to the apartment. Cat starts contemplating how nice it might be to have an apartment to herself, and Sam says she has experience in that area. Cat is confused, saying that she thought Sam lived with her mother. Sam says that living with her mother is a lot like living alone.  Dice returns with the scissors and bags for Sam's hair. They realize the kids aren't with them. Dice mentions that he just saw them at Inside Out Burger. They rush over to see that the kids are being chased by the manager. The manager passes out from exhaustion caused by chasing the kids, and Sam and Cat work together to revive him by using a creative form of CPR. As a way to thank them, the manager allows the two to have free cheeseburgers from the restaurant for a lifetime.

With the kids safe and a new burger discount, they return to the apartment, where Cat plays video games with the kids while Dice procures three bags of hair from Sam. The mother of the kids comes back. While the kids explicitly tell her everything, Sam and Cat manage to censor these events by saying it is all part of a video game. The mother pays Sam $150 on the spot, and asks if they can babysit them again. Sam explains that she doesn't live there, but Cat accepts the opportunity.

As the family and Dice leave, Sam jokingly claims she will keep most of the money, but instead gives it all to Cat to support her as she will be living alone for a while. Sam gets ready to leave, but Cat tells her she thinks that they had fun together and hints at a possible future adventure between them. Sam says she doesn't have anywhere she needs to be, and Cat looks like she needs a roommate.

Cat asks her to stay with her in LA for a while and help her find a roommate, but Sam reveals she has already found Cat a roommate: Her! Cat is overjoyed as "This is the best day ever!" They end the day on a high note by riding on Sam's motorcycle on their way to eat at Inside Out Burger with Cat teasing Sam and Sam says "This is gonna be a long ride."

The opening scene shows Sam sleeping on the sofa bed. Cat comes in and decides to wake Sam up by jokingly poking Sam's tummy and yelling "Hi!" Sam hates this, so she attacks Cat, and tells her not to do that again.

Cat and Sam watch the latest episode of their favorite show That's a Drag! before Cat heads off to school. Right before Cat leaves, a man comes to their apartment after seeing their flyer for their babysitting service and asks them to babysit his sons that afternoon. Cat is so excited to have their first real customer, she accidentally reveals that she and Sam are very inexperienced. The man notices Cat's comments, but asks again if she and Sam will babysit. The two quickly agree to help him out.

Cat comes home from school crying because That's a Drag! had been cancelled, while Sam is furious over the show's cancellation because it was a big hit. In the midst of Cat's sobbing and hysterics, the kids they have to babysit, Ethan and Bob, arrive. Their father introduces them before leaving very promptly. Cat tries to ask him if there are any special instructions for taking care of the boys, but the man doesn't stay long enough to answer her and the girls are left with Bob and Ethan to take care of with no notices. Sam and Cat quickly discover that Ethan has a million questions for them, and Bob is very clingy, immediately attaching himself to Sam's legs. After a few minutes, Sam decides to take everyone to the studio where That's a Drag! is filmed.

Once they reach the studio, a security guard sees them and asks what they are doing there. Sam and Cat attempt to change the subject by learning his name, Cheb. He still doesn't go along with them and yet again asks what they are doing at the studio. Sam distracts him by saying his car is on fire, and then he runs out of the studio. Sam detaches Bob from herself by telling him that one of the men working on the set loves to cuddle. Bob goes to the man instantly and wraps around his leg instead of Sam's. Ethan says that he needs to go to the bathroom and asks Cat if she will go with him. She gently tells him no and points him in the right direction. Ethan worries what will happen if his zipper gets stuck. Sam bluntly tells him to yank on it if this happens, and Ethan heads off. With the boys distracted, Sam and Cat approach the producer, a man named Jeff Du Shell.

Cat stomps on his foot, angry at him for the show's cancellation. Sam tells Cat that the producer isn't the person who cancels the show. The producer tells Cat that he's tried everything he could do, but the show will remain cancelled. Cat is still upset and follows the producer to his car as he drives. He doesn't pay any attention to her pleading, so Cat flings herself onto the hood of Jeff's car as he tries to drive away. Cat ends up with her face pressed to the windshield while Jeff attempts to dislodge her using his windshield wipers. Cat is not deterred and stays firmly attached.

Meanwhile, Sam is still at the studio with both boys. Ethan returns from the bathroom, but Bob has gone missing. Sam asks if anyone has seen him, and one of the set designers points out that Bob has climbed into a nearby stage light. Sam angrily yells at Bob and tells him to come down. Bob just laughs. Sam asks him if he is going to make her come and get him. When Bob doesn't answer, Sam intervenes. She notices that the stage light is attached to a rope. She grabs what appears to be an axe and severs the rope with it, sending the stage light plummeting from the ceiling. Bob and the light fall to the ground. Sam rips the top off the light and lifts Bob out of it. He amazingly seems just fine, With Bob and Ethan in tow, Sam leaves the studio and heads back to the apartment. Cat appears a short while later. Sam asks Cat where she's been, and Cat tells her that she was on the hood of Jeff Du Shell's car trying to talk to him all the way to Santa Monica, which is about 17 miles from the apartment. She finally fell off when the car hit a speed bump. Saddened, Cat sits down on the couch and turns on That's a Drag! After one of the characters in the show says that at least they will always have a piece of their newly departed grandfather, Cat says she wishes she could have a piece of the show forever. This gives Sam an idea to help Cat cheer up. She asks Cat if she would mind watching the boys for a little while, and says she has to run an errand. Cat agrees hoping time with the boys will improve her mood. After Sam leaves, Cat decides to take the boys to Elderly Acres so she can visit her Nona.

Once Sam leaves the apartment, she asks Dice to come along to the That's a Drag! studio. She tells Dice she needs his help to take a lamp from set for Cat, so Cat can have a piece of the show to hold onto. Dice calls Sam sweet, which infuriates her, Sam says she will create a distraction while Dice gets the lamp and stuffs it down his pants. Sam instructs Dice to meet her outside in the parking lot afterwards. As a distraction, Sam squirts some ketchup on her arm and breaks some glass to make it look like she cut herself. A security guard catches Dice stealing, despite Sam's efforts to keep the set workers focused on her. She pretends to be the boss' assistant. She tells the men to do what she says and let Dice go outside or she will write their names down to report to her boss. In a sudden burst of inspiration, Sam asks the workers where all the props for the show are going. A worker tells her that they are taking the props to a storage warehouse. Sam tells them no, her boss told her to have everything shipped to an address she writes down. The address is for Cat's apartment. Sam then goes back to the apartment and sets up the whole place like the set of That's a Drag! to surprise Cat.

Cat returns home from Elderly Acres. She is ecstatic to see what Sam has done, but worried that Nona will be angry that all of her furniture is gone. (Sam had arranged to have Nona's furniture shipped to the storage warehouse where the That's a Drag! props were originally supposed to go.) Although Nona pops into the apartment, she does not notice that the furniture had changed. She simply asks if the lamp is new, and the girls deny that it is. Nona says she could swear something is different, but she can't put her finger on it

 Cat comes home from school to find Sam trying to finish an assignment of proof of four monthly hours of community service for online school. Her submission consists of clearly Photo Docked (photoshopped) pictures of herself feeding "homeless animals". Cat doesn't believe that these photos will get her a good mark, but the topic changes to that of a somewhat bland-tasting foreign fruit that Cat bought for Gwen and Ruby, two British girls they will babysit later, and then Sam brings up the fact that British kids like bibble, which makes Cat freak out.

When Gwen and Ruby arrive, Cat gets a text from Nona wanting her to help her set up a bingo game, so Sam goes to Elderly Acres to get Nona to sign her assignment form. However, in order to do so, Sam must actually do community service requirement to get the signature she needs. Nona asks Sam to help her set up a good bingo game because Nona desperately wants people to like it, and makes a deal that in return for Sam's cooperation, she will sign the form. Sam reluctantly obliges.

Dice then visits Cat, selling here a 'spife' (a hybrid of a spoon and a knife) and offers one to Gwen and Ruby. Gwen texts her uncle to see if she can buy one, but Dice sees that the phone is a PearPhone 6, which has not been released yet. They reveal that their father is the PearPhone owner and has all the new PearPhone months before the release for public. Dice asks if he can buy one, and Gwen eventually yes when he proposes to buy 5 phones for $500.

Back at Elderly Acres, Sam hosts a new bingo game named 'Extreme Bingo', but for the introduction, she set up extreme music for elders and a rapper. In about few minutes, Nona tells Sam all of the elders left. Later in the building, Gwen and Ruby sell the phones to Dice, but when he opens the box, he finds that it is filled with rocks. Cat sarcastically with her usual clueless tone notes that "they really changed the design".

Sam comes home and sees that Dice had fallen for the rock in the box trick. Sam realizes that they're con artists, and wants to help Dice get revenge, but Cat thinks it's a misunderstanding. When she arrives at their apartment, she is told by Gwen that she was sure there were phones in the box, but before the girls can return the money, Cat notices Ruby is eating bibble. They tell her that they have a big barrel of it, and Cat eagerly exchanges her bike to by the barrel of bibble. She opens it and finds cotton swabs. She tries to talk to Gwen and Ruby, but by this time, they are quite annoyed with the 'con artist' accusation and they spray her with a hose.

Sam thinks they're gullible and they all decide to get revenge on them, so Sam and Cat concoct a plan to con the con artists. Soon, Gwen and Ruby are walking past Sam and Cat's apartment, where they read off a dialogue about a bingo game in Elderly Acres. The reward is a flat screen TV worth over $3,000, and the lucky card is #54. The dialogue details that Sam, a scam expert, tries to convince an inexperienced and worried Cat to partake in a scam using the lucky card and take the TV.

At Elderly Acres that night, Sam has set up a tamer version of the previous night's bingo game, now dubbed 'Slightly Less Extreme Bingo', and announces the winning prize: the flat screen TV mentioned earlier. Ruby and Gwen arrive with Cat's bike and Sam reluctantly allows them to play. Nona is selling bingo cards, and Cat buys one from her. The card turns out to be #54, and upon hearing it, Gwen and Ruby try to buy it off Nona with a higher price. Gwen, Ruby, and Cat engage in a bidding war over the card. Finally, Gwen and Ruby make an accepted final offer of $500 for the card, much to Cat's dismay, and in the end of the bingo game, they win.

We are led to believe that as part of the plan, Cat will trick the girls into gambling away their winnings, but this abruptly seems to fall apart when the police arrive and say that it's illegal to have a bingo game's prize over $2,000. Cat even reveals it was Nona's idea to set the game up, which Nona denies. Afterwards, one of the cops drags Gwen and Ruby outside while the other prepares to arrest Sam, Cat and Nona, turning into a massive argument. As Gwen and Ruby are being led away, Cat smiles at them.

While Gwen and Ruby try to bargain with the cop not to get another jail sentence, everyone is mad at the other cop for trying to shut down the bingo game. Just then, Hank returns and says, "The British are gone!", revealing that everyone is part of the plot. Dice gets his money back, Cat gets her bike back, Sam gets her signature, and Dice gives spives to everyone.

Meanwhile, Gwen and Ruby are seen outside a dumpster. They frantically try to call out for someone to pick them up and take them home. Then someone yells, "Cut!" and they break the fourth wall by cheering about doing a Sam & Cat episode.